Description

Microcystin La is a potent cyclic heptapeptide hepatotoxin produced by certain species of freshwater cyanobacteria. This compound is of critical importance for research and analytical applications, particularly in the fields of environmental monitoring, toxicology, and water safety. It serves as a primary reference standard for the detection and quantification of microcystin variants in water samples, making it essential for laboratories in the environmental, pharmaceutical, and public health sectors.

Application

• Environmental Monitoring & Water Safety: Used as a certified reference material for the analysis of cyanobacterial toxins in drinking water, reservoirs, and recreational water bodies.
• Toxicological Research: Employed in studies investigating the mechanisms of hepatotoxicity, oxidative stress, and tumor promotion associated with microcystin exposure.
• Analytical Method Development & Validation: Serves as a critical standard for calibrating equipment and validating methods in HPLC, LC-MS/MS, and ELISA test kits.
• Quality Control & Assurance: Used by manufacturers of diagnostic kits and testing laboratories to ensure the accuracy and reliability of microcystin detection assays.
• Regulatory Compliance Testing: Essential for testing against global water quality guidelines set by organizations like the WHO, EPA, and EFSA.
• Academic & Pharmaceutical Research: Utilized in biochemical research to study protein phosphatase inhibition and its cellular effects.

Basic Information

Item	Detail
Product Name	Microcystin La
CAS No.	96180-79-9
Molecular Formula	C₄₉H₇₄N₁₀O₁₂
Molecular Weight	995.2 g/mol
Synonyms	Microcystin-LA; MC-LA; [Dha⁷]Microcystin-LR; Cyanoginosin LA; Toxin T17; (2S,3S,4E,6E,8S,9S)-9-[(2S)-2-Methyl-1-oxo-3-[(2S,3S,5S,6R)-3,5-dihydroxy-6-methyloxan-2-yl]oxypropyl]-4,6,8-trimethyl-2-[[(2S)-1-[(2S,3S,4S,5S,6S)-3,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-methyl-1-oxopentan-2-yl]carbamoyl]-12-[(2S)-2-methylbut-3-en-2-yl]-1,7-dioxa-12-azacyclopentadec-4-ene-3,5,11,15-tetrone
EINECS	Contact for details

Quality Control

Our Microcystin La is produced and handled under strict quality protocols to ensure the highest standards of purity and stability for research and analytical use. Each batch is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing purity, identification, and chromatographic data to support your research integrity and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥95% (Area Percent)
Water Content (KF)	≤5.0%
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.