Description

3-tert-Butyldimethylsilyloxybenzaldehyde is a protected benzaldehyde derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which shields the phenolic hydroxyl during multi-step synthesis, enabling selective reactions on the aldehyde functionality. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing complex molecules, including active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing organic electronic materials.
• Fine Chemical & Fragrance Intermediate: Employed in the multi-step synthesis of specialty aromatics and flavor & fragrance compounds.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Peptide & Polymer Chemistry: Used in the synthesis of monomers and protected intermediates for specialized polymers.

Basic Information

Product Name	3-tert-Butyldimethylsilyloxybenzaldehyde
CAS No.	96013-95-5
Molecular Formula	C₁₃H₂₀O₂Si
Molecular Weight	236.39 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]benzaldehyde; 3-(tert-Butyldimethylsiloxy)benzaldehyde; 3-Hydroxybenzaldehyde TBDMS ether; 3-TBDMS-O-Benzaldehyde; Benzaldehyde, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 3-(tert-Butyldimethylsilyloxy)benzaldehyde; 3-TBDMS protected salicylaldehyde derivative
EINECS	Contact for details

Quality Control

Our 3-tert-Butyldimethylsilyloxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.