Description

3-(Trifluoromethyl)Butyraldehyde is a versatile fluorinated aldehyde intermediate of significant interest in advanced organic synthesis. Its value lies in the unique reactivity of the aldehyde group combined with the stability and lipophilicity imparted by the trifluoromethyl moiety, enabling the construction of complex molecules with tailored properties. This compound is essential for R&D chemists and process developers in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate fluorine into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated side chains to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer & Resin Modifier: Incorporated to create specialty polymers with enhanced chemical resistance, lower surface energy, and improved weatherability.
• Organic Synthesis Reagent: A valuable reagent for nucleophilic addition reactions, reductive amination, and as a precursor for heterocyclic compounds in academic and industrial research.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing novel fluorinated aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	3-(Trifluoromethyl)Butyraldehyde
CAS No.	95853-69-3
Molecular Formula	C5H7F3O
Molecular Weight	140.10 g/mol
Synonyms	4,4,4-Trifluorobutanal; 4,4,4-Trifluorobutyraldehyde; 3-(Trifluoromethyl)butanal; Butanal, 4,4,4-trifluoro-; γ,γ,γ-Trifluorobutyraldehyde; 4,4,4-Trifluoro-1-butanal; 3-Trifluoromethylbutyraldehyde; 4,4,4-Trifluorobutanaldehyde
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Butyraldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.