Description

Ethyl 3-Methyl-4,4,4-Trifluorobutyrate is a high-value fluorinated ester building block, prized for its unique trifluoromethyl group which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where the introduction of fluorine atoms is a key strategy for optimizing bioactivity and product performance. It serves as a critical intermediate for research and production chemists in the fine chemical, agrochemical, and pharmaceutical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring a trifluoromethylated side chain for improved pharmacokinetic properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine moiety enhances biological activity and environmental stability.
• Liquid Crystal & Electronic Chemicals: Acts as a fluorinated building block in the synthesis of specialty materials for display technologies and electronic applications.
• Organic Synthesis & Research: Serves as a versatile reagent in academic and industrial R&D labs for constructing complex fluorinated organic molecules.
• Flavor & Fragrance Industry: Potential use in the synthesis of novel fluorinated aroma chemicals, though specific applications require regulatory evaluation.

Basic Information

Product Name	Ethyl 3-Methyl-4,4,4-Trifluorobutyrate
CAS No.	95853-67-1
Molecular Formula	C7H11F3O2
Molecular Weight	184.16 g/mol
Synonyms	Ethyl 3-Methyl-4,4,4-Trifluorobutanoate; 4,4,4-Trifluoro-3-methylbutyric Acid Ethyl Ester; 3-Methyl-4,4,4-trifluorobutanoic acid ethyl ester; Butanoic acid, 4,4,4-trifluoro-3-methyl-, ethyl ester; Ethyl 4,4,4-trifluoro-3-methylbutyrate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Methyl-4,4,4-Trifluorobutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.