Description

2-Bromo-2,2-Difluoro-N,n-Dimethylacetamide CAS NO 95776-69-5 is a versatile fluorinated acetamide derivative, serving as a key building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine atoms, makes it a valuable reagent for introducing difluoroacetamide motifs and for further functionalization via nucleophilic substitution. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluoromethyl or gem-difluoro functional groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the difluoroacetamide moiety can enhance biological activity.
• Material Science Research: Employed as a monomer or modifying agent in the development of specialty polymers and fluorinated materials with unique properties.
• Organic Synthesis Reagent: Functions as an electrophilic reagent for the introduction of the -COCF2Br group, enabling the construction of complex molecular architectures in medicinal and process chemistry.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.

Basic Information

Product Name	2-Bromo-2,2-Difluoro-N,n-Dimethylacetamide
CAS No.	95776-69-5
Molecular Formula	C4H6BrF2NO
Molecular Weight	202.00 g/mol
Synonyms	N,N-Dimethyl-2-bromo-2,2-difluoroacetamide; 2-Bromo-2,2-difluoro-N,N-dimethylacetamide; Acetamide, 2-bromo-2,2-difluoro-N,N-dimethyl-; 2-Bromo-2,2-difluoroacetdimethylamide; α-Bromo-α,α-difluoro-N,N-dimethylacetamide; Bromodifluoroacetic Acid Dimethylamide; N,N-Dimethylbromodifluoroacetamide
EINECS	Contact for details

Quality Control

Our 2-Bromo-2,2-Difluoro-N,n-Dimethylacetamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.