Description

1-(Difluoromethyl)-1H-1,2,4-Triazole is a specialized heterocyclic building block featuring a reactive difluoromethyl group attached to the triazole ring. This compound is valued for its role as a key intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where the difluoromethyl moiety can impart desirable metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development teams in the crop protection and life science industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A critical synthon for developing new-generation fungicides, herbicides, and insecticides that require the difluoromethyl group for enhanced efficacy and environmental profile.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of potential drug candidates, particularly in areas where fluorine substitution is beneficial for binding affinity and pharmacokinetics.
• Material Science Research: Employed in the development of specialty polymers, ligands, or functional materials that incorporate triazole chemistry.
• Chemical Synthesis: Serves as a versatile reagent for introducing the -CHF2 group into more complex molecular architectures in organic and fluorochemical research.

Basic Information

Product Name	1-(Difluoromethyl)-1H-1,2,4-Triazole
CAS No.	95759-01-6
Molecular Formula	C3H3F2N3
Molecular Weight	119.07 g/mol
Synonyms	1-(Difluoromethyl)-1H-1,2,4-triazole; 1H-1,2,4-Triazole, 1-(difluoromethyl)-; Difluoromethyl-1,2,4-triazole; 1,2,4-Triazole, 1-(difluoromethyl)-; 95759-01-6
EINECS	Contact for details

Quality Control

Our 1-(Difluoromethyl)-1H-1,2,4-Triazole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.