Description

Ethanone, 2-Chloro-1-[4-(Trifluoromethyl)Phenyl]- is a high-purity, specialized aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity conferred by the combination of a chloroacetyl group and a trifluoromethylphenyl moiety, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique optical or electronic properties.
• Liquid Crystal & OLED Materials: Acts as a building block for creating advanced organic electronic materials due to its specific molecular geometry and electronic characteristics.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for methodological studies, including cross-coupling reactions and the development of new catalytic processes.

Basic Information

Product Name	Ethanone, 2-Chloro-1-[4-(Trifluoromethyl)Phenyl]-
CAS No.	95727-89-2
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	2-Chloro-1-[4-(trifluoromethyl)phenyl]ethanone; 2-Chloro-4'-trifluoromethylacetophenone; 4'-(Trifluoromethyl)-2-chloroacetophenone; 2-Chloro-1-(4-trifluoromethylphenyl)ethan-1-one; α-Chloro-4-(trifluoromethyl)acetophenone; p-Trifluoromethyl-ω-chloroacetophenone; 95727-89-2
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Chloro-1-[4-(Trifluoromethyl)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.