Description

1-(2,6-Difluorophenyl)Butan-1-One is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the 2,6-difluorophenyl moiety, a key structural feature that can modulate the biological activity and physicochemical properties of target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl group enhances stability and bioavailability.
• Material Science Research: Serves as a precursor for synthesizing specialized monomers, ligands for catalysis, or fluorinated liquid crystals.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	1-(2,6-Difluorophenyl)Butan-1-One
CAS No.	95727-77-8
Molecular Formula	C₁₀H₁₀F₂O
Molecular Weight	184.18 g/mol
Synonyms	1-Butanone, 1-(2,6-difluorophenyl)-; 2',6'-Difluorobutyrophenone; 1-(2,6-Difluorophenyl)-1-butanone; Butyrophenone, 2,6-difluoro-; 95727-77-8; 2,6-Difluorobutyrophenone
EINECS	Contact for details

Quality Control

Our production of 1-(2,6-Difluorophenyl)Butan-1-One adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.