Description

1-Bromo-2-Nitro-4-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethoxy and nitro substituents, which are critical for modulating the electronic properties and bioactivity of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing complex, high-performance dyes and pigments with specific light-fastness properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination, enabling complex molecular architecture construction.

Basic Information

Product Name	1-Bromo-2-Nitro-4-(Trifluoromethoxy)Benzene
CAS No.	95668-21-6
Molecular Formula	C7H3BrF3NO3
Molecular Weight	285.99 g/mol
Synonyms	2-Nitro-4-(trifluoromethoxy)bromobenzene; 4-Bromo-3-nitro(trifluoromethoxy)benzene; 1-Bromo-2-nitro-4-(trifluoromethoxy)benzene; Benzene, 1-bromo-2-nitro-4-(trifluoromethoxy)-; 95668-21-6; 4-(Trifluoromethoxy)-2-nitro-1-bromobenzene; 3-Nitro-4-bromo(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Nitro-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.