Description

3-Carboxy-2,3-Epoxypropionyl-Leucylamido-(4-Acetamido)Butane is a specialized, high-purity synthetic intermediate featuring a complex molecular architecture combining epoxy, carboxy, and peptide-like amido functionalities. This compound is valued for its role as a critical building block in advanced organic synthesis, enabling the development of novel compounds with targeted biological or material properties. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery and the synthesis of sophisticated molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzymatic pathways.
• Peptidomimetic Research: Serves as a constrained scaffold in medicinal chemistry for designing and synthesizing peptide analogs with enhanced stability and bioavailability.
• Bioconjugation Chemistry: Utilized in the development of linker molecules for antibody-drug conjugates (ADCs) or other targeted therapeutic agents due to its reactive epoxy and carboxyl groups.
• Agrochemical Synthesis: Employed as an advanced intermediate in the research and development of new-generation herbicides or plant growth regulators.
• Chemical Biology Probes: Used to create activity-based probes for studying enzyme function and mechanism in biochemical research.
• Material Science: Investigated as a monomer or cross-linking agent for creating novel polymers with specific functional properties.

Basic Information

Item	Detail
Product Name	3-Carboxy-2,3-Epoxypropionyl-Leucylamido-(4-Acetamido)Butane
CAS No.	95499-84-6
Molecular Formula	C16H25N3O7
Molecular Weight	371.39 g/mol
Synonyms	N-[4-(Acetylamino)butyl]-2-[(2S)-2-amino-4-methylpentanoyl]amino-3-oxiran-2-yl-3-oxopropanamide; 3-Carboxy-2,3-epoxypropionyl-L-leucylamido-(4-acetamido)butane; (2S)-2-[[(2S)-2-Amino-4-methyl-1-oxopentyl]amino]-3-(oxiran-2-yl)-3-oxopropanoic acid N-(4-acetamidobutyl)amide; Epoxypropionyl-Leu-Abu-NHAc derivative; A specialized epoxy-peptide conjugate.
EINECS	Contact for details

Quality Control

Every batch of 3-Carboxy-2,3-Epoxypropionyl-Leucylamido-(4-Acetamido)Butane is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.