Description

3-Chloro-6-Fluoro-2-(Trifluoromethyl)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block, essential for synthesizing advanced chemical intermediates. Its unique structure, featuring chlorine, fluorine, and trifluoromethyl substituents, provides critical electronic and steric properties for developing novel active compounds. This compound is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where its aromatic and fluorinated characteristics modify material properties.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Chloro-6-Fluoro-2-(Trifluoromethyl)Benzaldehyde
CAS No.	95399-94-3
Molecular Formula	C8H3ClF4O
Molecular Weight	226.56 g/mol
Synonyms	2-(Trifluoromethyl)-3-chloro-6-fluorobenzaldehyde; 3-Chloro-6-fluoro-2-trifluoromethylbenzaldehyde; 3-Chloro-6-fluoro-alpha,alpha,α-trifluoro-o-tolualdehyde; Benzaldehyde, 3-chloro-6-fluoro-2-(trifluoromethyl)-; 95399-94-3; 3-Chloro-6-fluoro-2-(trifluoromethyl)benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-6-Fluoro-2-(Trifluoromethyl)Benzaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and scale-up. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.