Description

Methyl 2-(3,5-Bis(Trifluoromethyl)Phenyl)Acetate is a high-value fluorinated aromatic ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring two electron-withdrawing trifluoromethyl groups, makes it indispensable for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process developers in the pharmaceutical and agrochemical sectors for applications in catalysis, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Catalyst & Ligand Development: Serves as a precursor for creating specialized phosphine or nitrogen-based ligands used in transition metal catalysis, including cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and polymers for specialty materials, such as fluorinated polyimides or liquid crystals, offering unique thermal and optical properties.
• Organic Synthesis: A versatile reagent for introducing the 3,5-bis(trifluoromethyl)phenyl moiety into target molecules via ester hydrolysis, transesterification, or further functional group transformations.

Basic Information

Product Name	Methyl 2-(3,5-Bis(Trifluoromethyl)Phenyl)Acetate
CAS No.	95299-16-4
Molecular Formula	C12H8F6O2
Molecular Weight	298.18 g/mol
Synonyms	Methyl [3,5-Bis(trifluoromethyl)phenyl]acetate; Acetic acid, 2-[3,5-bis(trifluoromethyl)phenyl]-, methyl ester; Methyl (3,5-bis(trifluoromethyl)phenyl)acetate; 2-(3,5-Bis(trifluoromethyl)phenyl)acetic acid methyl ester; Methyl α-(3,5-Bis(trifluoromethyl)phenyl)acetate; 3,5-Bis(trifluoromethyl)benzeneacetic acid methyl ester; Methyl 3,5-bis(trifluoromethyl)phenylacetate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(3,5-Bis(Trifluoromethyl)Phenyl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA), detailing identity, purity, and impurity profiles, is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly sealed due to the compound's sensitivity to moisture and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.