Description

3-(4-Fluorophenylamino)-3-Oxopropanoic Acid is a specialized organic compound featuring a fluorinated aniline moiety linked to a β-keto acid structure. This unique molecular architecture makes it a valuable high-purity building block and intermediate for advanced chemical synthesis. It is primarily utilized by pharmaceutical research and development organizations, agrochemical innovators, and fine chemical manufacturers requiring precise fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic or photonic properties.
• Bioconjugation Chemistry: The reactive keto-acid group allows for use in linking molecules to proteins or other biomolecules for diagnostic or therapeutic applications.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and medicinal chemistry explorations within university and corporate laboratories.

Basic Information

Product Name	3-(4-Fluorophenylamino)-3-Oxopropanoic Acid
CAS No.	95262-10-5
Molecular Formula	C9H8FNO3
Molecular Weight	197.16 g/mol
Synonyms	3-[(4-Fluorophenyl)amino]-3-oxopropanoic acid; 3-(4-Fluoroanilino)-3-oxopropanoic acid; N-(4-Fluorophenyl)malonamic acid; 4-Fluoro-N-(2-carboxyacetyl)aniline; 95262-10-5; 3-Oxo-3-[(4-fluorophenyl)amino]propanoic acid; β-Keto-N-(4-fluorophenyl)alanine derivative
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluorophenylamino)-3-Oxopropanoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.