Description

(-)-13,20-Epoxy-1β,11β,12α,14,15β,21-Hexahydroxypicrasa-3-Ene-2,16-Dione CAS NO 95258-14-3 is a highly functionalized, complex natural product derivative belonging to the quassinoid class of compounds. This compound is of significant interest for its potential as a key intermediate in advanced organic synthesis and for its biological activity profile. It is primarily sought after by research and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors. Its intricate polycyclic structure with multiple hydroxyl and carbonyl groups makes it a valuable scaffold for developing novel bioactive molecules.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or a lead compound for the synthesis of novel therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.
• Bioactivity Screening: Used as a standard or test compound in high-throughput screening assays to evaluate cytotoxicity, anti-proliferative, and other pharmacological activities.
• Natural Product Chemistry: Acts as a reference standard for the isolation, identification, and structural elucidation of related quassinoids and terpenoids from plant extracts.
• Chemical Synthesis: Employed as a sophisticated chiral building block for the total synthesis of complex natural products and for studying novel organic reaction methodologies.
• Agrochemical Research: Investigated for potential use as a precursor in developing new plant growth regulators or biopesticides with novel modes of action.
• Academic Research: Utilized in university and institutional labs for advanced studies in medicinal chemistry, synthetic organic chemistry, and chemical biology.

Basic Information

Product Name	(-)-13,20-Epoxy-1β,11β,12α,14,15β,21-Hexahydroxypicrasa-3-Ene-2,16-Dione
CAS No.	95258-14-3
Molecular Formula	C20H26O10
Molecular Weight	426.42 g/mol
Synonyms	13,20-Epoxy-1β,11β,12α,14,15β,21-hexahydroxypicrasa-3-ene-2,16-dione; (-)-Picrasane derivative; Quassinoid derivative; 2,16-Dioxo-13,20-epoxy-1β,11β,12α,14,15β,21-hexahydroxypicras-3-ene; Bruceine analogue; Complex oxygenated terpenoid
EINECS	Contact for details

Quality Control

Our (-)-13,20-Epoxy-1β,11β,12α,14,15β,21-Hexahydroxypicrasa-3-Ene-2,16-Dione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.