Description

Ethyl 4-Fluorocyclohexane-1-Carboxylate is a versatile fluorinated cyclohexane derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine, which can dramatically alter the physical, chemical, and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability, bioavailability, and binding affinity. Its unique structure makes it a key intermediate for probing structure-activity relationships and developing new fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and performance.
• Organic Synthesis Building Block: Employed in medicinal chemistry for lead optimization and in academic research for constructing complex, fluorinated molecular architectures.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing novel fluorinated aroma chemicals with unique olfactory properties.
• Polymer Modification: Can be used to introduce fluorine into polymer backbones or side chains to enhance material properties like chemical resistance and surface energy.

Basic Information

Product Name	Ethyl 4-Fluorocyclohexane-1-Carboxylate
CAS No.	95233-40-2
Molecular Formula	C9H15FO2
Molecular Weight	174.21 g/mol
Synonyms	4-Fluorocyclohexanecarboxylic Acid Ethyl Ester; Ethyl 4-Fluorocyclohexanecarboxylate; trans/cis-Ethyl 4-Fluorocyclohexanecarboxylate; 4-Fluoro-1-cyclohexanecarboxylic Acid Ethyl Ester; 1-Carbethoxy-4-fluorocyclohexane; Ethyl 4-Fluorocyclohexylcarboxylate; 95233-40-2; 4-Fluorocyclohexylcarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluorocyclohexane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support compliance with relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (typical ≥98.5%)
Water Content (KF)	≤ 0.5%
Isomer Ratio (cis/trans)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.