Description

3-(2-Fluorophenyl)-3,4-Dihydroisocoumarin is a specialized fluorinated isocoumarin derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which serves as a versatile precursor for developing novel pharmacologically active compounds and functional materials. This intermediate is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents, leveraging the bioactivity of the isocoumarin core and the fluorine atom's influence on bioavailability.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic systems, lactones, and fluorinated aromatic compounds in academic and industrial R&D laboratories.
• Material Science Precursor: Investigated for the synthesis of specialty polymers, liquid crystals, or organic electronic materials where the fluorinated aromatic system can modify physical and electronic properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-(2-Fluorophenyl)-3,4-Dihydroisocoumarin
CAS No.	95217-42-8
Molecular Formula	C15H11FO2
Molecular Weight	242.25 g/mol
Synonyms	3-(2-Fluorophenyl)-3,4-dihydro-1H-isochromen-1-one; 3-(2-Fluorophenyl)-3,4-dihydro-2H-1-benzopyran-1-one; 2-Fluorophenyl-3,4-dihydroisocoumarin; 3,4-Dihydro-3-(2-fluorophenyl)-1H-2-benzopyran-1-one; 3-(o-Fluorophenyl)-3,4-dihydroisocoumarin; 95217-42-8; AI3-52362
EINECS	Contact for details

Quality Control

Our 3-(2-Fluorophenyl)-3,4-Dihydroisocoumarin is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.