Description

4-Chloro-2-Ethynyl-1-Methoxybenzene is a high-purity, specialized aromatic compound featuring both chloro and ethynyl functional groups on a methoxybenzene scaffold. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the creation of novel active compounds and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Sonogashira) and click chemistry due to its reactive ethynyl group.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific electronic properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies.

Basic Information

Product Name	4-Chloro-2-Ethynyl-1-Methoxybenzene
CAS No.	95186-47-3
Molecular Formula	C9H7ClO
Molecular Weight	166.60 g/mol
Synonyms	1-Chloro-4-ethynyl-2-methoxybenzene; 2-Ethynyl-4-chloroanisole; 4-Chloro-2-ethynylanisole; 4-Chloro-2-ethynylmethoxybenzene; 2-Methoxy-5-chlorophenylacetylene; 5-Chloro-2-methoxyphenylacetylene
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Ethynyl-1-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.