Description

4-Methoxybicyclo[2.2.2]octane-1-carboxaldehyde is a specialized bicyclic aldehyde derivative, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique, rigid molecular framework is prized for introducing conformational constraints and specific stereochemistry into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fragrance industries, where it is used to develop novel active ingredients and complex aroma chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those requiring constrained, three-dimensional architectures.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where its bicyclic structure can enhance biological activity and stability.
• Fragrance & Flavor Chemistry: Serves as a precursor for high-value aroma chemicals, contributing unique olfactory properties due to its methoxy-substituted bicyclic core.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored physical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including asymmetric synthesis and catalysis research.
• Ligand & Catalyst Development: The aldehyde functionality and rigid backbone make it suitable for constructing novel chiral ligands and organocatalysts.

Basic Information

Product Name	4-Methoxybicyclo[2.2.2]octane-1-carboxaldehyde
CAS No.	94994-28-2
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	4-Methoxybicyclo[2.2.2]octane-1-carbaldehyde; 1-Formyl-4-methoxybicyclo[2.2.2]octane; 4-Methoxy-2,6-dioxabicyclo[2.2.2]octane-1-carboxaldehyde (related); Bicyclo[2.2.2]octane-1-carboxaldehyde, 4-methoxy-; 4-Methoxy-BCO-CHO
EINECS	Contact for details

Quality Control

Our production of 4-Methoxybicyclo[2.2.2]octane-1-carboxaldehyde adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.