Description

{4-Fluorobicyclo[2.2.2]Octan-1-Yl}Methanol is a specialized fluorinated organic building block characterized by its rigid bicyclic framework. This compound is valued for its unique steric and electronic properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated, conformationally constrained motifs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides, where the fluorinated bicyclic structure can enhance biological activity and environmental stability.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, or advanced organic frameworks that benefit from its rigid, fluorinated core.
• Organic Synthesis Building Block: Acts as a versatile precursor in academic and industrial laboratories for constructing complex natural product analogs and other fine chemicals.
• Ligand and Catalyst Development: Utilized in the design of novel chiral ligands or organocatalysts where the bicyclo[2.2.2]octane skeleton provides a stable, three-dimensional scaffold.

Basic Information

Product Name	{4-Fluorobicyclo[2.2.2]Octan-1-Yl}Methanol
CAS No.	94994-16-8
Molecular Formula	C9H15FO
Molecular Weight	158.21 g/mol
Synonyms	4-Fluorobicyclo[2.2.2]octane-1-methanol; (4-Fluorobicyclo[2.2.2]oct-1-yl)methanol; 1-(Hydroxymethyl)-4-fluorobicyclo[2.2.2]octane; 4-Fluoro-1-bicyclo[2.2.2]octylmethanol; 4-Fluoro-1-hydroxymethylbicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our {4-Fluorobicyclo[2.2.2]Octan-1-Yl}Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.