Description

2-Bromo-1-(5-chloropyridin-2-yl)ethanone is a versatile and high-value brominated ketone building block in organic synthesis. This compound is critical for the efficient construction of complex heterocyclic scaffolds, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing pyridine and fused heterocyclic systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive bromoacetyl group.
• Chemical Biology Probe Development: Serves as a versatile electrophile for labeling proteins or modifying biomolecules in probe and linker synthesis.
• Material Science Research: Potential precursor for the synthesis of specialized ligands, catalysts, or organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized pyridine derivatives.

Basic Information

Product Name	2-Bromo-1-(5-chloropyridin-2-yl)ethanone
CAS No.	94952-47-3
Molecular Formula	C7H5BrClNO
Molecular Weight	234.48 g/mol
Synonyms	2-Bromo-1-(5-chloro-2-pyridinyl)ethanone; 1-(5-Chloro-2-pyridinyl)-2-bromoethanone; 2-Bromo-1-(5-chloropyridin-2-yl)ethan-1-one; 5-Chloro-2-(bromoacetyl)pyridine; α-Bromo-5-chloropyridin-2-yl methyl ketone; 94952-47-3; Ethanone, 2-bromo-1-(5-chloro-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5-chloropyridin-2-yl)ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.