Description

S-(1,1,2,2-Tetrafluoroethyl)Cysteine is a specialized fluorinated amino acid derivative, a key building block in advanced chemical synthesis. This compound matters for its unique ability to introduce a highly fluorinated moiety into peptides and other biomolecules, significantly altering their physicochemical properties. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients, as well as by companies in the material science sector exploring fluorinated polymers and surface modifiers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly for targeted therapies and imaging agents.
• Agrochemical Research: Used to create novel fluorinated pesticides and herbicides with potentially enhanced stability and bioavailability.
• Peptide Modification: Enables the site-specific incorporation of fluorine into peptides to study structure-activity relationships and improve metabolic stability.
• Bioconjugation Chemistry: Serves as a handle for creating stable, fluorinated linkages in antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science: A monomer or modifier for synthesizing specialty fluorinated polymers with unique surface properties.
• Biochemical Tool Development: Used in proteomics and enzymology to create activity-based probes and enzyme inhibitors.

Basic Information

Product Name	S-(1,1,2,2-Tetrafluoroethyl)Cysteine
CAS No.	94840-66-1
Molecular Formula	C5H7F4NO2S
Molecular Weight	221.17 g/mol
Synonyms	L-Cysteine, S-(1,1,2,2-tetrafluoroethyl)-; (R)-2-Amino-3-((1,1,2,2-tetrafluoroethyl)thio)propanoic acid; Tetrafluoroethylcysteine; S-Tetrafluoroethyl-L-cysteine; 2-Amino-3-[(1,1,2,2-tetrafluoroethyl)sulfanyl]propanoic acid; NSC 339586; Fluorinated cysteine derivative
EINECS	Contact for details

Quality Control

Our S-(1,1,2,2-Tetrafluoroethyl)Cysteine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. For long-term storage, consider refrigeration (2-8°C) under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.