Description

3,4-Methylenedioxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those with benzodioxole or substituted phenyl moieties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl coupling steps.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and semiconductors, where controlled aryl-aryl bond formation is crucial.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological processes and target engagement.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis due to the stability offered by the pinacol ester protecting group.

Basic Information

Product Name	3,4-Methylenedioxyphenylboronic Acid, Pinacol Ester
CAS No.	94838-82-1
Molecular Formula	C₁₃H₁₇BO₄
Molecular Weight	248.08 g/mol
Synonyms	1,3,2-Benzodioxaborole, 2-(3,4-methylenedioxyphenyl)-4,4,5,5-tetramethyl-; 2-(Benzo[d][1,3]dioxol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzodioxole; 3,4-(Methylenedioxy)phenylboronic Acid Pinacol Ester; Piperonylboronic Acid Pinacol Ester; 3,4-Methylenedioxyphenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3,4-Methylenedioxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.