Description

4,4,4-Trifluoro-2-Hydroxylimino-3-Oxobutyric Acid Ethyl Ester is a specialized fluorinated building block featuring a unique trifluoromethyl ketone oxime ester structure. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides with enhanced activity and environmental profiles.
• Fluorinated Material Precursor: Serves as a starting material for synthesizing specialty fluorinated polymers and advanced materials.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex molecules via reactions involving its ketone, oxime, and ester functional groups.
• Chemical Biology Probe Development: Utilized in the design of fluorinated probes and ligands for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	4,4,4-Trifluoro-2-Hydroxylimino-3-Oxobutyric Acid Ethyl Ester
CAS No.	94609-23-1
Molecular Formula	C6H6F3NO4
Molecular Weight	213.11 g/mol
Synonyms	Ethyl 4,4,4-trifluoro-2-(hydroxyimino)-3-oxobutanoate; Ethyl 4,4,4-trifluoro-3-oxo-2-(hydroxyimino)butyrate; 4,4,4-Trifluoro-3-oxo-2-butenoic acid ethyl ester oxime; TFHOBE; Ethyl 4,4,4-trifluoroacetoacetate oxime; 2-(Hydroxyimino)-4,4,4-trifluoro-3-oxobutyric acid ethyl ester; 94609-23-1
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-2-Hydroxylimino-3-Oxobutyric Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.