Description

2-(Bromomethyl)-1,3-Dichloro-5-Methoxybenzene is a halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromomethyl and dichloro substituents on a methoxybenzene core, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and insecticides, where the dichloro and bromomethyl groups offer reactive handles for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful for creating tagged molecules or photoaffinity labels in biochemical research due to its reactive bromomethyl group.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	2-(Bromomethyl)-1,3-Dichloro-5-Methoxybenzene
CAS No.	94278-70-3
Molecular Formula	C8H7BrCl2O
Molecular Weight	270.95 g/mol
Synonyms	1,3-Dichloro-5-methoxy-2-(bromomethyl)benzene; 2-Bromomethyl-1,3-dichloro-5-methoxybenzene; 5-Methoxy-1,3-dichloro-2-(bromomethyl)benzene; 1-(Bromomethyl)-3,5-dichloro-4-methoxybenzene; 3,5-Dichloro-4-methoxybenzyl bromide; (3,5-Dichloro-4-methoxyphenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-1,3-Dichloro-5-Methoxybenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We are committed to meeting the stringent requirements of research and development as well as cGMP standards for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.