Description

5-(tert-Butyl)-2,3,4,5,6,7-Hexahydro-2-Methyl-1H-Inden-1-One is a high-purity, synthetically derived indanone derivative that serves as a critical advanced intermediate in complex organic syntheses. Its unique sterically hindered structure makes it a valuable building block for constructing specialized molecular architectures. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

This versatile indanone intermediate is employed in a variety of high-value synthetic pathways, including:

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel therapeutic compounds, including central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Building block for developing new generation pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fragrance and Flavor Chemistry: Intermediate for creating complex musk-like or woody aroma chemicals due to its indanone backbone.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Organic Synthesis Research: A valuable substrate for methodological studies in ring-forming reactions and functional group transformations.

Basic Information

Product Name	5-(tert-Butyl)-2,3,4,5,6,7-Hexahydro-2-Methyl-1H-Inden-1-One
CAS No.	94278-41-8
Molecular Formula	C₁₄H₂₂O
Molecular Weight	206.33 g/mol
Synonyms	5-tert-Butyl-2-methyl-1-indanone; 2-Methyl-5-tert-butylindan-1-one; 5-tert-Butyl-2-methylindan-1-one; 1-Indanone, 2,3,4,5,6,7-hexahydro-5-(1,1-dimethylethyl)-2-methyl-; 5-(1,1-Dimethylethyl)-2-methyl-2,3,4,5,6,7-hexahydro-1H-inden-1-one; 2-Methyl-5-(tert-butyl)indan-1-one; tert-Butyl methyl indanone
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyl)-2,3,4,5,6,7-Hexahydro-2-Methyl-1H-Inden-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.