Description

(R)-Boroval-(+)-Pinanediol-Cf3Co2H is a high-purity, chiral organoboron reagent featuring a pinanediol auxiliary and a trifluoromethyl carboxylate group. This compound is a critical building block in asymmetric synthesis, enabling the precise introduction of chiral centers and fluorinated motifs into complex molecules. It is essential for research chemists and process development scientists in the pharmaceutical and advanced materials sectors who require reliable, enantiomerically pure intermediates for API development and specialty chemical manufacturing.

Application

• As a chiral boron reagent for asymmetric Suzuki-Miyaura cross-coupling reactions in pharmaceutical synthesis.
• Key intermediate in the development of fluorinated active pharmaceutical ingredients (APIs) and agrochemicals.
• Used in catalytic asymmetric synthesis for constructing complex, enantiomerically pure molecular architectures.
• Precursor for organometallic catalysts and ligands used in fine chemical production.
• Building block for advanced materials research, including liquid crystals and organic electronics.
• Reagent in methodology development within academic and industrial R&D laboratories.

Basic Information

Product Name	(R)-Boroval-(+)-Pinanediol-Cf3Co2H
CAS No.	94242-81-6
Molecular Formula	C₁₈H₂₈BF₃O₄
Molecular Weight	376.22 g/mol
Synonyms	(R)-[(+)-Pinanediolato](2,2,2-Trifluoroethoxy)borane; (R)-2,2,2-Trifluoroethyl Pinanediol Boronate; (R)-Trifluoroethyl Boronic Acid Pinanediol Ester; (R)-α-(Trifluoroethoxy)boronic Acid Pinanediol Ester; (R)-Boronic Acid, (2,2,2-trifluoroethoxy)-, 2,3-pinanediol ester; (R)-B-[(+)-Pinanediolato]-2,2,2-trifluoroethoxoborane
EINECS	Contact for details

Quality Control

Every batch of (R)-Boroval-(+)-Pinanediol-Cf3Co2H is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity. Our products are suitable for demanding applications in pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/NMR), enantiomeric excess, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon/nitrogen) to maintain stability and purity. Keep away from incompatible materials such as strong oxidizers and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.