Description

2-Methyl-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Propan-1-Amine is a versatile and highly valuable protected aminoboronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient and selective construction of complex molecules, particularly through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and process development. We supply this key intermediate with a focus on consistent quality, reliable purity, and secure global logistics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing amine and boronic acid functionalities used in Suzuki-Miyaura cross-couplings.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides that require the incorporation of specific amine-boronate motifs.
• Organic Ligand & Catalyst Development: Used to create novel ligands for transition metal catalysts or as a functional handle in organocatalysis research.
• Material Science & Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers, dendrimers, or boron-containing advanced materials.
• Chemical Biology & Bioconjugation: Utilized in the design and synthesis of probes, tags, and linkers for labeling biomolecules due to its reactive amine and protected boronic acid groups.
• Academic & Industrial R&D: Serves as a fundamental building block in medicinal chemistry and process chemistry laboratories for exploring new synthetic routes.

Basic Information

Product Name	2-Methyl-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Propan-1-Amine
CAS No.	94242-78-1
Molecular Formula	C10H22BNO2
Molecular Weight	199.10 g/mol
Synonyms	1-Amino-2-methylpropylboronic acid pinacol ester; (1-Amino-2-methylpropyl)boronic acid pinacol ester; 2-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-1-amine; 2-Methyl-1-(pinacolatoboryl)propan-1-amine; Isobutylamine boronic acid pinacol ester; (2-Methylpropyl)aminoboronic acid pinacol ester; B-(1-Amino-2-methylpropyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Propan-1-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide detailed Certificates of Analysis (COA) upon request, documenting all critical specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to minimize moisture uptake and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.