Description

Dde-Oh CAS NO 94142-97-9 is a specialized chemical compound widely recognized as a key building block in advanced organic synthesis. Its primary value lies in its role as a versatile protecting group reagent, particularly for amines, enabling complex multi-step reactions with high selectivity and yield. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and peptide synthesis industries who require precise molecular control for developing new active pharmaceutical ingredients (APIs) and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): Used as a crucial reagent for the temporary protection of amino groups, facilitating the sequential assembly of peptide chains.
• Orthogonal Protection Strategies: Enables complex multi-step organic synthesis where selective deprotection is required, often in conjunction with Fmoc and Boc groups.
• Pharmaceutical Intermediate Production: Serves as a key building block in the research and development of novel therapeutic compounds and APIs.
• Bioconjugation Chemistry: Employed in the site-specific modification of proteins, antibodies, and other biomolecules for drug delivery and diagnostic applications.
• Combinatorial Chemistry: Utilized in the generation of diverse chemical libraries for high-throughput screening in drug discovery.
• Glycopeptide and Glycoprotein Synthesis: Applied in the challenging synthesis of glycosylated peptides and proteins.

Basic Information

Product Name	Dde-Oh
CAS No.	94142-97-9
Molecular Formula	C14H15NO4
Molecular Weight	261.27 g/mol
Synonyms	1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl; Dde-OH; N-(1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl)-Dde; 4,4-Dimethyl-2,6-dioxocyclohexylidene ethylamine derivative; N-1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethylamine; Dde protecting group reagent; (E)-1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutan-1-ol (common misnomer for the active ester forms).
EINECS	Contact for details

Quality Control

Our Dde-Oh is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.