Description

Ethanone, 2-Chloro-1-(2,4-Difluorophenyl)-2-Fluoro- (9Ci) is a high-purity fluorinated aromatic ketone building block, identified by CAS number 94119-78-5. This compound is valued for its precise molecular structure, which is critical for introducing specific halogenated motifs into complex molecules during synthesis. It is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, where its difluorophenyl and chlorofluoroacetone functionalities enable fine-tuning of biological activity and physicochemical properties.

Application

This specialized chemical intermediate serves key roles in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in antifungal and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluorophenyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where fluorinated aromatic units impart unique thermal and chemical resistance.
• Chemical R&D: Serves as a versatile substrate for exploring new fluorination reactions and cross-coupling methodologies in process chemistry.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(2,4-Difluorophenyl)-2-Fluoro- (9Ci)
CAS No.	94119-78-5
Molecular Formula	C8H4ClF3O
Molecular Weight	208.56 g/mol
Synonyms	2-Chloro-1-(2,4-difluorophenyl)-2-fluoroethanone; 2-Chloro-2-fluoro-1-(2,4-difluorophenyl)ethanone; 1-(2,4-Difluorophenyl)-2-chloro-2-fluoroethanone; α-Chloro-α-fluoro-2,4-difluoroacetophenone; 2,4-Difluoro-α-chloro-α-fluoroacetophenone; 94119-78-5; FC-DFA Ketone Intermediate
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2-Chloro-1-(2,4-Difluorophenyl)-2-Fluoro- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous standards required for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.