Description

4'-(Trifluoromethoxy)Propiophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its core value lies in the unique reactivity of the propiophenone scaffold combined with the electron-withdrawing and lipophilicity-enhancing trifluoromethoxy group. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group improves biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials requiring specific dipole moments and thermal stability.
• Advanced Polymer Modification: Incorporated into specialty polymer chains to alter solubility, chemical resistance, and material properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development, such as in cross-coupling reactions or carbonyl chemistry.
• Fluorine Chemistry Library Building: A valuable compound for creating focused libraries of fluorinated molecules for high-throughput screening in drug discovery.

Basic Information

Item	Detail
Product Name	4'-(Trifluoromethoxy)Propiophenone
CAS No.	94108-55-1
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]propan-1-one; 4'-Trifluoromethoxypropiophenone; 4-(Trifluoromethoxy)propiophenone; p-Trifluoromethoxypropiophenone; 1-Propanone, 1-[4-(trifluoromethoxy)phenyl]-; Propiophenone, 4'-(trifluoromethoxy)-; α-Ethyl-4-(trifluoromethoxy)benzaldehyde (tautomer); TFMPP (common abbreviation)
EINECS	Contact for details

Quality Control

Our 4'-(Trifluoromethoxy)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to consistent quality and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.