Description

5-Fluoro-1-Tetralone is a versatile fluorinated organic building block and a key synthetic intermediate. Its value lies in the strategic incorporation of a fluorine atom into the tetralone scaffold, which is crucial for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the fluorine atom enhances metabolic stability and bioavailability.
• Material Science: Acts as a monomer or building block for advanced polymers and liquid crystals with specific electronic properties.
• Organic Synthesis: A valuable substrate for various reactions, including Grignard additions, reductions, and ring-forming transformations to create complex polycyclic structures.
• Fluorine Chemistry Studies: Employed in academic and industrial research to study the effects of fluorine substitution on aromatic systems and ketone reactivity.

Basic Information

Product Name	5-Fluoro-1-Tetralone
CAS No.	93742-85-9
Molecular Formula	C₁₀H₉FO
Molecular Weight	164.18 g/mol
Synonyms	5-Fluoro-3,4-dihydronaphthalen-1(2H)-one; 5-Fluoro-α-tetralone; 1(2H)-Naphthalenone, 5-fluoro-3,4-dihydro-; 5-Fluorotetralone; 5-Fluoro-1-oxotetralin; 5-Fluoro-3,4-dihydro-1(2H)-naphthalenone
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Tetralone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from laboratory to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.