Description

Cyclohexane, 1-Fluoro-2-Nitro-, trans- (9Ci) is a fluorinated nitrocyclohexane derivative, a valuable and versatile building block in advanced organic synthesis. Its unique structure, featuring both fluorine and nitro substituents in a specific stereochemical configuration, enables precise molecular modifications critical for developing novel compounds. This intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Acts as a fluorinated core structure for synthesizing specialty chemicals used in electronic displays and optoelectronic devices.
• Organofluorine Chemistry Research: A critical reagent for studying fluorine introduction strategies and the stereoelectronic effects of the fluoro-nitro motif.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing complex, fluorinated aromatic and alicyclic systems.
• Polymer Modification: Employed to introduce fluorinated nitrocyclohexyl groups into polymer backbones, altering physical properties like solubility and thermal stability.

Basic Information

Item	Details
Product Name	Cyclohexane, 1-Fluoro-2-Nitro-, trans- (9Ci)
CAS No.	93696-75-4
Molecular Formula	C6H10FNO2
Molecular Weight	147.15 g/mol
Synonyms	trans-1-Fluoro-2-nitrocyclohexane; (1R,2R)-1-Fluoro-2-nitrocyclohexane; (1S,2S)-1-Fluoro-2-nitrocyclohexane; 1-Fluoro-2-nitrocyclohexane, trans-; trans-2-Nitro-1-fluorocyclohexane; Fluoronitrocyclohexane; 93696-75-4; 1-Fluoro-2-nitro-cyclohexane
EINECS	Contact for details

Quality Control

Every batch of Cyclohexane, 1-Fluoro-2-Nitro-, trans- (9Ci) is produced and analyzed under strict quality management protocols to ensure high purity, consistency, and traceability. Our quality assurance includes comprehensive analytical testing via HPLC, GC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential reactivity with strong bases, the container should be kept in the original packaging until use. Keep away from incompatible materials such as strong alkalis and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.