Description

Methyl 3,3,3-Trifluoro-Dl-Lactate is a versatile fluorinated building block and chiral synthon of significant interest in advanced organic synthesis. Its value lies in the introduction of the trifluoromethyl group, which can dramatically alter the physicochemical properties of target molecules, enhancing metabolic stability, lipophilicity, and bioavailability. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Advanced Polymer Modifiers: Incorporated to create specialty fluoropolymers with unique surface properties, chemical resistance, and durability.
• Asymmetric Catalysis & Ligand Development: Employed as a substrate or precursor in the development of chiral catalysts and ligands for stereoselective reactions.
• Proteolysis-Targeting Chimera (PROTAC) & Degrader Development: A valuable linker component in the design of targeted protein degradation therapeutics.

Basic Information

Product Name	Methyl 3,3,3-Trifluoro-Dl-Lactate
CAS No.	93496-85-6
Molecular Formula	C4H5F3O3
Molecular Weight	158.08 g/mol
Synonyms	Methyl 2-hydroxy-3,3,3-trifluoropropanoate; 3,3,3-Trifluoro-2-hydroxypropanoic acid methyl ester; DL-Methyl 3,3,3-trifluorolactate; Methyl 3,3,3-trifluoro-2-hydroxypropionate; 2-Hydroxy-3,3,3-trifluoropropionic acid methyl ester; Methyl (±)-3,3,3-trifluorolactate; 3,3,3-Trifluorolactic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3,3,3-Trifluoro-Dl-Lactate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure identity, potency, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-Racemate
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.