Description

3-(Methoxy)Tetrafluoropropionic Acid is a specialized fluorinated organic acid characterized by its unique methoxy-tetrafluoroalkyl chain. This compound is valued for its strong acidity and the introduction of fluorine atoms, which can dramatically alter the physical, chemical, and biological properties of target molecules. It serves as a critical building block and intermediate for researchers and manufacturers in advanced chemical synthesis. Primary demand originates from the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to create novel compounds with enhanced stability, bioavailability, or specific activity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated monomers and polymers used in liquid crystal displays (LCDs) and dielectric materials.
• Organic Synthesis & Catalysis: Acts as a strong acid catalyst or a reagent in various fluorination and functionalization reactions in research and process chemistry.
• Surface Active Agents: Potential building block for creating fluorinated surfactants with low surface tension for specialized coatings and fire-fighting foams.

Basic Information

Product Name	3-(Methoxy)Tetrafluoropropionic Acid
CAS No.	93449-21-9
Molecular Formula	C₄H₄F₄O₃
Molecular Weight	176.07 g/mol
Synonyms	3-Methoxytetrafluoropropanoic Acid; 2,2,3,3-Tetrafluoro-3-methoxypropionic Acid; α,α,β,β-Tetrafluoro-β-methoxypropionic Acid; Tetrafluoro-3-methoxypropionic Acid; 93449-21-9; 3-Methoxy-2,2,3,3-tetrafluoropropionic acid; Propanoic acid, 2,2,3,3-tetrafluoro-3-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 3-(Methoxy)Tetrafluoropropionic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements of your application. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with shipment. Our quality commitment supports compliance in cGMP, ISO, and other relevant regulatory frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container must be kept tightly sealed due to the compound's nature as a strong acid/organic solvent and its light-sensitive properties.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.