Description

2-Hydroxy-5-(Trifluoromethoxy)Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block distinguished by its unique trifluoromethoxy and phenolic hydroxyl substituents. This compound matters for its critical role in synthesizing advanced pharmaceutical intermediates and agrochemicals, where its specific substitution pattern imparts desirable biological activity and metabolic stability. Industrial researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical sectors need this material for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and steric properties.
• Chemical Research & Development: A versatile building block for academic and industrial R&D in medicinal chemistry and organic synthesis.

Basic Information

Product Name	2-Hydroxy-5-(Trifluoromethoxy)Benzaldehyde
CAS No.	93249-62-8
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	5-(Trifluoromethoxy)salicylaldehyde; 2-Hydroxy-5-(trifluoromethoxy)benzaldehyde; Salicylaldehyde, 5-(trifluoromethoxy)-; 5-Trifluoromethoxysalicylaldehyde; Benzaldehyde, 2-hydroxy-5-(trifluoromethoxy)-; 2-Hydroxy-5-trifluoromethoxybenzaldehyde; 5-(Trifluoromethoxy)-2-hydroxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-(Trifluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support compliance with relevant regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.