Description

2-(Bromomethyl)-3-Nitrobenzonitrile is a versatile and high-value aromatic nitrile building block used in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and an electron-withdrawing nitro substituent, makes it a critical intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing fused heterocycles like quinazolines, benzimidazoles, and other nitrogen-containing bioactive compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the nitrile and nitro groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Cross-Coupling Reactions: The bromomethyl moiety acts as an electrophilic site for nucleophilic substitution or as a handle for further functionalization via palladium-catalyzed reactions.

Basic Information

Product Name	2-(Bromomethyl)-3-Nitrobenzonitrile
CAS No.	93213-75-3
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	3-Nitro-2-(bromomethyl)benzonitrile; 2-Bromomethyl-3-nitrobenzonitrile; Benzonitrile, 2-(bromomethyl)-3-nitro-; α-Bromo-3-nitro-o-tolunitrile; 2-(Bromomethyl)-3-nitrobenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-3-Nitrobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.