Description

2-Bromo-3-Fluoropropiophenone is a specialized fluorinated and brominated aromatic ketone, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique halogenated structure makes it a critical building block for constructing complex molecules, particularly in pharmaceutical research and fine chemical synthesis. This compound is essential for medicinal chemists and R&D laboratories focused on developing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with fluorinated active components.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis.
• Material Science Research: Building block for synthesizing fluorinated organic compounds used in advanced polymers and liquid crystals.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-Bromo-3-Fluoropropiophenone
CAS No.	92821-83-5
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	1-(2-Bromo-3-fluorophenyl)propan-1-one; 2-Bromo-3-fluoropropiophenone; 2'-Bromo-3'-fluoropropiophenone; 1-Propanone, 1-(2-bromo-3-fluorophenyl)-; α-Bromo-β-fluoropropiophenone; 2-Bromo-3-fluorophenyl ethyl ketone; 2-Bromo-3-fluoro-1-phenylpropan-1-one
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoropropiophenone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our commitment to reliable supply and batch-to-batch reproducibility supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.