Description

Ethanone, 1-(2,5-Dimethylphenyl)-2-Fluoro- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), crop protection agents, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, potentially targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development, such as studying fluorination effects and cross-coupling reactions.
• Fine Chemical Manufacturing: Integral to multi-step synthetic routes for producing high-value, complex fluorinated organic compounds for various industrial applications.

Basic Information

Product Name	Ethanone, 1-(2,5-Dimethylphenyl)-2-Fluoro- (9Ci)
CAS No.	92778-28-4
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	2'-Fluoro-2,5-dimethylacetophenone; 1-(2,5-Dimethylphenyl)-2-fluoroethanone; 2-Fluoro-1-(2,5-dimethylphenyl)ethan-1-one; 2,5-Dimethyl-2'-fluoroacetophenone; α-Fluoro-2',5'-dimethylacetophenone; 2-Fluoro-2',5'-dimethylacetophenone; 92778-28-4; 1-(2,5-Dimethylphenyl)-2-fluoroethan-1-one
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2,5-Dimethylphenyl)-2-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Purity (HPLC/GC)	≥99.0% (High Purity Grade)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.