Description

Cyclobutanecarboxylic Acid, 3-Amino-2,2-Dimethyl-, cis- (9Ci) is a high-purity, stereochemically defined building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need this material for constructing complex molecular architectures, particularly in the synthesis of proprietary drug candidates and specialty agrochemicals. Its defined cis-configuration and functional groups offer precise control over the stereochemistry of final products.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific spatial orientation is crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into the backbone of peptide analogs to enhance metabolic stability and binding affinity.
• Material Science: Potential monomer or additive for creating specialized polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and process development.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-Amino-2,2-Dimethyl-, cis- (9Ci)
CAS No.	92772-95-7
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	cis-3-Amino-2,2-dimethylcyclobutanecarboxylic Acid; (1R,3S)-3-Amino-2,2-dimethylcyclobutanecarboxylic Acid (and other stereoisomers); 2,2-Dimethyl-3-aminocyclobutanecarboxylic Acid; 3-Amino-2,2-dimethylcyclobutanecarboxylic acid, cis-; Aminodimethylcyclobutanecarboxylic Acid; ADCB Acid; Cyclobutane-1-carboxylic acid, 3-amino-2,2-dimethyl-, cis-
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 3-Amino-2,2-Dimethyl-, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support compliance needs for cGMP, ISO, and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.