Description

1-Bromo-3,3,4,4,4-Pentafluoro-2-Butanone is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its unique reactivity profile, combining a reactive bromine atom with a highly fluorinated ketone moiety, making it a valuable precursor for introducing perfluoroalkyl groups into target molecules. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as in materials science for creating specialty polymers and surface modifiers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the incorporation of trifluoromethyl and related perfluoroalkyl groups into drug candidates, enhancing metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where fluorine atoms are critical for bioactivity and environmental persistence.
• Fluorinated Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty fluoropolymers with unique thermal, chemical, and surface properties.
• Liquid Crystal & Electronic Materials: Employed in the creation of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.
• Surface Modification Reagent: Utilized to impart oil- and water-repellent characteristics to various surfaces and textiles.
• Organic Synthesis Building Block: Provides a versatile handle for nucleophilic substitution and subsequent transformations in complex molecule construction.

Basic Information

Product Name	1-Bromo-3,3,4,4,4-Pentafluoro-2-Butanone
CAS No.	92737-01-4
Molecular Formula	C4H2BrF5O
Molecular Weight	240.96 g/mol
Synonyms	3,3,4,4,4-Pentafluoro-1-bromobutan-2-one; 1-Bromo-3,3,4,4,4-pentafluorobutan-2-one; 2-Butanone, 1-bromo-3,3,4,4,4-pentafluoro-; Pentafluoro-1-bromo-2-butanone; Bromopentafluorobutanone
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,3,4,4,4-Pentafluoro-2-Butanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to handle under an inert atmosphere for extended storage periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.8 g/mL
Refractive Index (n20D)	~1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.