Description

1β,11β,12α,20-Tetrahydroxypicras-3-Ene-2,16-Dione is a highly functionalized, complex natural product derivative belonging to the quassinoid class of compounds. This compound is valued for its intricate molecular architecture, which serves as a critical scaffold for advanced research and development in medicinal chemistry. It is primarily sought by pharmaceutical research organizations and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in anti-cancer and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a reference standard or a starting material for structure-activity relationship (SAR) studies to develop new quassinoid-based therapeutics.
• Natural Product Synthesis: Acts as an advanced intermediate in the total or semi-synthesis of complex natural products for biological evaluation.
• Biochemical Tool Compound: Employed in biochemical assays to study specific cellular pathways and protein interactions.
• Fine Chemical Production: Utilized in the manufacture of high-value, specialized chemicals for research and development purposes.

Basic Information

Product Name	1β,11β,12α,20-Tetrahydroxypicras-3-Ene-2,16-Dione
CAS No.	92678-86-9
Molecular Formula	C20H28O6
Molecular Weight	364.43 g/mol
Synonyms	Picras-3-ene-2,16-dione, 1,11,12,20-tetrahydroxy-, (1β,11β,12α)-; 1β,11β,12α,20-Tetrahydroxypicras-3-en-2,16-dione; Quassinoid derivative; NSC 339586; A member of the Simaroubaceae family lactones.
EINECS	Contact for details

Quality Control

Our 1β,11β,12α,20-Tetrahydroxypicras-3-Ene-2,16-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.