Description

2-Azabicyclo[2.2.1]Heptane-3-Carboxaldehyde, 2-(Trifluoroacetyl)-, Endo- (9Ci) is a specialized bicyclic organic compound featuring a trifluoroacetyl-protected amine and an aldehyde functional group, serving as a high-value chiral building block. This compound matters for its role in facilitating the synthesis of complex, stereochemically defined molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the 2-azabicyclo[2.2.1]heptane scaffold into target molecules.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization due to its rigid, three-dimensional structure.
• Agrochemical Research: Used in the development of new pesticides and herbicides that require specific chiral configurations for biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in homogeneous catalysis.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and chemical biology studies.

Basic Information

Item	Detail
Product Name	2-Azabicyclo[2.2.1]Heptane-3-Carboxaldehyde, 2-(Trifluoroacetyl)-, Endo- (9Ci)
CAS No.	92591-89-4
Molecular Formula	C9H10F3NO2
Molecular Weight	221.18 g/mol
Synonyms	Endo-2-(Trifluoroacetyl)-2-azabicyclo[2.2.1]heptane-3-carboxaldehyde; 2-Azabicyclo[2.2.1]heptane-3-carboxaldehyde, 2-(trifluoroacetyl)-, endo-; 2-(Trifluoroacetyl)-2-azabicyclo[2.2.1]heptane-3-carbaldehyde, endo-; 2-Azabicyclo[2.2.1]heptane-3-carbaldehyde, 2-(trifluoroacetyl)-, (1R,2S,4R)-rel-; (1R,2S,4R)-2-(Trifluoroacetyl)-2-azabicyclo[2.2.1]heptane-3-carbaldehyde; endo-N-(Trifluoroacetyl)norcamphor-3-carboxaldehyde; Bicyclo[2.2.1]heptane-3-carboxaldehyde, 2-(trifluoroacetyl)-2-aza-, endo-
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.1]Heptane-3-Carboxaldehyde, 2-(Trifluoroacetyl)-, Endo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This material is easily oxidized and light-sensitive. Keep container tightly sealed in a cool, dry, and well-ventilated place. Separate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (endo isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.