Description

9-Deoxy-9A-Aza-9A-Methyl-9A-Homoerythromycin A is a chemically modified derivative of the macrolide antibiotic erythromycin, representing a key intermediate in the synthesis of advanced azalide antibiotics. This compound is critical for pharmaceutical R&D and manufacturing, offering a versatile scaffold for developing novel antimicrobial agents with potentially improved pharmacokinetic profiles. It is primarily utilized by pharmaceutical research laboratories, fine chemical manufacturers, and academic institutions engaged in the development of next-generation antibacterial therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of advanced azalide antibiotics, such as certain ketolides.
• Antibacterial Research: Serves as a core structural template for medicinal chemistry programs aimed at discovering new macrolide derivatives with activity against resistant bacterial strains.
• Biochemical Studies: Used in research to study structure-activity relationships (SAR) and the mechanism of action of macrolide antibiotics.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and impurity profiling.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for the commercial production of specialized antibiotic active pharmaceutical ingredients (APIs).

Basic Information

Product Name	9-Deoxy-9A-Aza-9A-Methyl-9A-Homoerythromycin A
CAS No.	92470-27-4
Molecular Formula	C38H72N2O12
Molecular Weight	748.99 g/mol
Synonyms	9-Deoxy-9a-aza-9a-methyl-9a-homoerythromycin A; 9a-Aza-9a-methyl-9a-homoerythromycin A 9-deoxy; 9a-Aza-9a-methyl-9a-homoerythromycin A, 9-deoxy-; 9a-Aza-9a-methyl-9a-homoerythromycin A, 9-deoxy- (8CI); 9a-Aza-9a-methyl-9a-homoerythromycin A, 9-deoxy- (8CI); 9a-Aza-9a-methyl-9a-homoerythromycin A, 9-deoxy- (8CI); 9a-Aza-9a-methyl-9a-homoerythromycin A, 9-deoxy- (8CI); 9a-Aza-9a-methyl-9a-homoerythromycin A, 9-deoxy- (8CI)
EINECS	Contact for details

Quality Control

Our 9-Deoxy-9A-Aza-9A-Methyl-9A-Homoerythromycin A is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.