Description

tert-Butyl Oxirane-2-Carboxylate is a high-value chiral glycidyl ester derivative, serving as a versatile and critical building block in advanced organic synthesis. Its epoxide functionality and protected carboxylate group make it an essential precursor for constructing complex molecules with high stereochemical control. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and specialty intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers, protease inhibitors, and other enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty epoxy resins and functional polymers.
• Liquid Crystal & OLED Materials: Building block for advanced electronic materials requiring specific stereochemistry.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in catalytic reactions to induce chirality.
• Academic & R&D: Used in medicinal chemistry research for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	tert-Butyl Oxirane-2-Carboxylate
CAS No.	92223-80-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	tert-Butyl Glycidate; Glycidic Acid tert-Butyl Ester; 2-Oxiranecarboxylic Acid, 1,1-Dimethylethyl Ester; (Oxiran-2-yl)carboxylic Acid tert-Butyl Ester; tert-Butyl 2,3-Epoxypropionate; tert-Butyl Epoxypropionate; TBGE; tert-Butyl (±)-Glycidate
EINECS	Contact for details

Quality Control

Our tert-Butyl Oxirane-2-Carboxylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.