Description

5,5-Dimethyl-2-(2-Methylphenyl)-1,3,2-Dioxaborinane is a specialized organoboron compound that serves as a valuable synthetic intermediate. Its primary value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling characteristics for complex organic synthesis. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors, where it is utilized in key cross-coupling reactions to construct novel molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and agrochemicals.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for creating complex, sterically hindered molecules.
• Advanced Material Synthesis: Employed in the production of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a precursor for novel boron-containing ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and enzyme activity.
• Agrochemical Research: Acts as a building block for novel herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	5,5-Dimethyl-2-(2-Methylphenyl)-1,3,2-Dioxaborinane
CAS No.	91994-11-5
Molecular Formula	C13H19BO2
Molecular Weight	218.10 g/mol
Synonyms	2-(2-Methylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; o-Tolyl-5,5-dimethyl-1,3,2-dioxaborinane; 2-Methylphenyl-5,5-dimethyl-1,3,2-dioxaborinane; (2-Methylphenyl)boronic acid 5,5-dimethyl-1,3,2-dioxaborinane ester; 2-Methylbenzeneboronic acid cyclic ester with 2,2-dimethyl-1,3-propanediol
EINECS	Contact for details

Quality Control

Our 5,5-Dimethyl-2-(2-Methylphenyl)-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.