Description

4,4,5,5-Tetramethyl-2-[(1E)-1-Methyl-1-Propen-1-Yl]-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex organic frameworks. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for synthesizing novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A premier reagent for forming carbon-carbon bonds between aryl/vinyl halides and this boronic ester derivative.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Manufacturing: Serves as a key building block for creating novel herbicides, fungicides, and insecticides.
• Advanced Materials Development: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
• Ligand and Catalyst Preparation: Useful for constructing complex ligand frameworks in organometallic chemistry.
• Chemical Biology & Probe Development: Facilitates the labeling and modification of biomolecules for research purposes.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[(1E)-1-Methyl-1-Propen-1-Yl]-1,3,2-Dioxaborolane
CAS No.	91890-02-7
Molecular Formula	C12H21BO2
Molecular Weight	208.11 g/mol
Synonyms	2-[(1E)-1-Methylprop-1-en-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(1-Methylprop-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; trans-2-(1-Methyl-1-propenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-1-Methyl-1-propenylboronic acid pinacol ester; Pinacol (E)-1-methylprop-1-en-1-ylboronate; 91890-02-7
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[(1E)-1-Methyl-1-Propen-1-Yl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.