Description

(Z)-2-Buten-2-Ylboronic Acid Pinacol Ester is a high-purity, stereodefined boronic ester building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily used by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing complex (Z)-alkene-containing molecules in drug discovery and material science.
• Pharmaceutical Intermediate Synthesis: Used in the production of stereospecific active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Agrochemical Research: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific stereochemistry.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and organometallic complexes.
• Advanced Material Precursors: Utilized in the creation of organic semiconductors, liquid crystals, and polymers with defined geometric structures.
• Chemical Biology Probes: Acts as a handle for bioconjugation and the synthesis of activity-based probes for target identification.

Basic Information

Product Name	(Z)-2-Buten-2-Ylboronic Acid Pinacol Ester
CAS No.	91890-00-5
Molecular Formula	C10H19BO2
Molecular Weight	182.07 g/mol
Synonyms	(Z)-1-Methyl-1-propenylboronic Acid Pinacol Ester; (Z)-2-Buten-2-ylboronic Acid Pinacol Ester; (Z)-1-Methylvinylboronic Acid Pinacol Ester; (Z)-1-Propen-1-ylboronic Acid, 1,1-Dimethylethyl Ester; (Z)-2-Buten-2-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (Z)-1-Methylvinylboronate; (Z)-1-Methylvinylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our (Z)-2-Buten-2-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by NMR (1H, 11B, 13C), GC or HPLC analysis to confirm identity, isomeric purity (Z/E ratio), and assay. Certificates of Analysis (COA) with full analytical data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for prolonged use or when opening a new container to prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Isomeric Purity (Z-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.