Description

Cyclopropanecarboxylic Acid, 3-Ethynyl-2,2-Dimethyl-, Methyl Ester, (1R-Cis)- is a high-value, chiral synthetic intermediate characterized by its cyclopropane ring and ethynyl functionality. This compound matters for its role in enabling the synthesis of complex, biologically active molecules, offering a unique three-dimensional scaffold and reactive handle for further chemical elaboration. Pharmaceutical and agrochemical research organizations need this specific stereoisomer to develop novel active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane moiety can contribute to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with unique structural properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways due to its reactive alkyne group for click chemistry.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 3-Ethynyl-2,2-Dimethyl-, Methyl Ester, (1R-Cis)-
CAS No.	91726-63-5
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(1R,3S)-3-Ethynyl-2,2-dimethylcyclopropanecarboxylic acid methyl ester; Methyl (1R,3S)-3-ethynyl-2,2-dimethylcyclopropanecarboxylate; (1R-cis)-3-Ethynyl-2,2-dimethylcyclopropanecarboxylic acid methyl ester; cis-3-Ethynyl-2,2-dimethylcyclopropanecarboxylic acid methyl ester (1R,3S enantiomer); 3-Ethynyl-2,2-dimethylcyclopropanecarboxylic acid methyl ester, (1R-cis)-; (1R,3S)-rel-3-Ethynyl-2,2-dimethylcyclopropanecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 3-Ethynyl-2,2-Dimethyl-, Methyl Ester, (1R-Cis)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.