Description

Methyl Propiolate CAS NO 922-67-8 is a versatile and highly reactive alkyne ester, serving as a crucial building block in organic synthesis. Its terminal acetylene group and ester functionality make it an essential reagent for constructing complex molecular architectures through cycloaddition and coupling reactions. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating active ingredients and novel polymers.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of heterocyclic compounds, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers, coatings, and adhesives with tailored properties.
• Chemical Research & Development: A fundamental reagent for [3+2] and other cycloaddition reactions, as well as Sonogashira and other metal-catalyzed cross-couplings in lab-scale and pilot-scale synthesis.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Methyl Propiolate
CAS No.	922-67-8
Molecular Formula	C4H4O2
Molecular Weight	84.07 g/mol
Synonyms	Propiolic Acid Methyl Ester; Methyl 2-Propynoate; Methyl Acetylene Carboxylate; 2-Propynoic Acid Methyl Ester; Methyl Propynoate; Methyl Propargylate; Methyl Propiolate (stabilized)
EINECS	213-077-8

Quality Control

Our Methyl Propiolate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR), to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and polymerization risk. Keep away from heat, sparks, open flames, and oxidizing agents. Due to its highly volatile nature, containers must be kept tightly sealed and handled with appropriate precautions to prevent vapor accumulation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.