Description

Methyl 4-Bromobenzoate is a versatile aromatic ester building block, widely recognized for its utility in advanced organic synthesis. Its primary value lies in serving as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research and development. This compound is essential for chemists and manufacturers in the life sciences, fine chemicals, and material science sectors who require a reliable, high-purity reagent for coupling reactions and derivatization.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or substituted benzoate moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the 4-bromophenyl group is a key structural element.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Reagent: Employed in esterification studies, as a protecting group, and for introducing the 4-bromobenzoyl fragment into larger molecular architectures.
• Chemical Research & Development: Used in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	Methyl 4-Bromobenzoate
CAS No.	619-42-1
Molecular Formula	C8H7BrO2
Molecular Weight	215.04 g/mol
Synonyms	4-Bromobenzoic acid methyl ester; Methyl p-bromobenzoate; p-Bromobenzoic acid methyl ester; Methyl 4-bromobenzenecarboxylate; Benzoic acid, 4-bromo-, methyl ester; Methyl ester of 4-bromobenzoic acid; MBBA (in specific contexts)
EINECS	210-592-9

Quality Control

Our Methyl 4-Bromobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents and bases. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.